Difference between Hirschprung disease and functional constipation
Both HD and FC are causes of constipation in children, HD being less common (incidence 1 in 5000). However, it is important to differentiate between the two as the management strategies are different for each of them. Hirschsprung disease Functional constipation Passage of meconium Delayed Normal (within 48 hour) Onset of symptoms < 1 year age > 1 year age Stool withholding no May be present Encopresis no May be present Abdominal distension May be present Usually not associated Failure to thrive Commonly present in delayed presentation Usually not a feature Enterocolitis As a complication of HD Not seen Digital rectal examination Tight grip of finger, empty rectum & Gush of explosive offensive stool as finger is taken out Stool in rectum Barium enema: Rectosigmoid ratio (R:S) < 1 > 1 Transitional zone present no RAIR (rectoanal inhibitory reflex) absent Present normally Rectal biopsy Ganglion cells absent present Nerve bundles hypertrophied normal...